Ketotifen, a mast cell blocker improves sperm motility in asthenospermic infertile men
نویسندگان
چکیده
منابع مشابه
P-4: Zaditen (Ketotifen), as Mast Cell Blocker, Improves Sperm Quality, Chromatin Integrity and Pregnancy Rate after Varicocelectomy
Background: Surgery is considered the most common choice for the treatment of male infertility with clinical varicocele. Increased numbers of mast cells (MCs) have been associated with different types of infertility, including varicocele. Despite there being different reports on improved fertility following administration of MC blockers, there is no report on the effect of a MC blocker on varic...
متن کاملSperm morphology, motility, and concentration in fertile and infertile men.
BACKGROUND Although semen analysis is routinely used to evaluate the male partner in infertile couples, sperm measurements that discriminate between fertile and infertile men are not well defined. METHODS We evaluated two semen specimens from each of the male partners in 765 infertile couples and 696 fertile couples at nine sites. The female partners in the infertile couples had normal result...
متن کاملTHE CORRELATION BETWEEN SPERM MORPHOLOGY AND MOTILITY IN FERTILE AND INFERTILE MEN
The swim-up procedure was used to collect a sperm fraction with improved motility and normal morphology from fertile and infertile semen samples. The untreated and swim-up fractions were analyzed with the Hamilton-Thorn Motility Analyser. Comparisons were made to see the effect of this sperm selection technique on sperm motility and morphology. They were then examined by transmission elect...
متن کاملEvaluation of sperm proteins in infertile men: a proteomic approach.
In this study, the sperm protein profile was compared between fertile and infertile men using 2-dimensional gel electrophoresis, liquid chromatography mass spectrometer analysis, and matrix-assisted laser desorption ionization-time-of-flight-mass spectrometry. Four unique proteins, semenogelin II precursor, prolactin-induced protein, clusterin isoform 1, and prostate-specific antigen isoform 1 ...
متن کاملA Correlation of Serum Inhibin with Sperm Count and Sperm Motility in Fertile and Infertile Males
Inhibin is produced by Sertoli cells of the testis, provides negative feedback on FSH secretion, and may prove to be an important marker for the functioning of seminiferous tubules. The purpose of this study was to examine the relationship between the spermatogenic function of the tests of subfertile men and the plasma concentrations of inhibin. The study was carried out on twenty infertile (or...
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ژورنال
عنوان ژورنال: Journal of Human Reproductive Sciences
سال: 2013
ISSN: 0974-1208
DOI: 10.4103/0974-1208.112373